Lapatinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral... more
Product information "Lapatinib"
Description: Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity. Lapatinib has antitumor activity and can be used to treat advanced or metastatic breast cancer with HER2 overexpression. Target: Autophagy, EGFR, Ferroptosis. Smiles: N(C=1C2=C(C=CC(=C2)C=3OC(CNCCS(C)(=O)=O)=CC3)N=CN1)C4=CC(Cl)=C(OCC5=CC(F)=CC=C5)C=C4. References: Wainberg ZA, et al. Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo. Clin Cancer Res. 2010 Mar 1,16(5):1509-19.
| Keywords: | GW572016, GSK572016 |
| Supplier: | TargetMol |
| Supplier-Nr: | T0078 |
Properties
| MW: | 581.06 D |
| Formula: | C29H26ClFN4O4S |
Database Information
| CAS : | 231277-92-2| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H319, H362, H413 |
| P Phrases: | P201, P260, P263, P264, P270, P273, P280, P305+351+338, P308+313, P337+313, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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