Lansoprazole sulfone

Lansoprazole sulfone is a phase I metabolite of lansoprazole (Cay-13627, Cay-21967, Cay-18235). Lansoprazole is a proton pump inhibitor that inactivates the hydrogen/potassium-stimulated ATPase pumps in parietal cells, thus inhibiting gastric acid secretion and increasing intragastric pH. Lansoprazole is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form lansoprazole sulfone.Formal Name: 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole. CAS Number: 131926-99-3. Synonyms: AG-1813. Molecular Formula: C16H14F3N3O3S. Formula Weight: 385.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, Ethanol: 5 mg/ml. lambdamax: 281 nm. SMILES: CC1=C(CS(C2=NC(C=CC=C3)=C3N2)(=O)=O)N=CC=C1OCC(F)(F)F. InChi Code: InChI=1S/C16H14F3N3O3S/c1-10-13(20-7-6-14(10)25-9-16(17,18)19)8-26(23,24)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22). InChi Key: TVMJMCGRSSSSDJ-UHFFFAOYSA-N.