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L-Valine-d8 is intended for use as an internal standard for the quantification of L-valine (Cay-38709) by GC- or LC-MS. L-Valine is a branched-chain essential amino acid that is obtained via the diet. It is considered glucogenic due to its catabolism that ultimately forms succinyl-CoA, which enters the citric acid cycle. A deficiency in branched-chain dehydrogenase, the enzyme that catabolizes valine, isoleucine, and leucine, leads to maple syrup urine disease, a disorder characterized by progressive ketoacidosis, failure to thrive, neurological dysfunction, and, potentially, death.Formal Name: L-valine-2,3,4,4,4,4',4',4'-d8. CAS Number: 35045-72-8. Synonyms: (+)-Valine, (S)-Valine. Molecular Formula: C5H3D8NO2. Formula Weight: 125.2. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): 1 mg/ml. SMILES: [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])[C@@](N)([2H])C(O)=O. InChi Code: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1/i1D3,2D3,3D,4D. InChi Key: KZSNJWFQEVHDMF-AYWPRJOCSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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