L-Asparagine

L-Asparagine is a non-essential amino acid. It is formed from L-aspartic acid and L-glutamine (Cay-23716) by asparagine synthetase (ASNS), and it is deamidated by L-asparaginase to produce L-aspartic acid and ammonia. L-Asparagine (0.3 mM) reverses ASNS siRNA knockdown-induced decreases in proliferation in a panel of six human cancer cell lines, indicating that both exogenous and endogenous L-asparagine promote proliferation of these cells. Formulations containing L-asparagine have been used as dietary supplements.CAS Number: 70-47-3. Synonyms: alpha-Aminosuccinic Acid, (-)-Asparagine, (S)-Asparagine, NSC 82391. Molecular Formula: C4H8N2O3. Formula Weight: 132.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: insolu, DMSO: insolu, Ethanol: insolu, PBS (pH 7.2): 5 mg/ml. SMILES: NC(C[C@H](N)C(O)=O)=O. InChi Code: InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1. InChi Key: DCXYFEDJOCDNAF-REOHCLBHSA-N.