KU-0060648
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: KU-0060648 is a dual inhibitor of DNA-PK and PI3Kalpha, PI3Kbeta, PI3Kdelta with... more
Product information "KU-0060648"
Description: KU-0060648 is a dual inhibitor of DNA-PK and PI3Kalpha, PI3Kbeta, PI3Kdelta with IC50 values of 8.6 nM, 4 nM, 0.5 nM, and 0.1 nM respectively, and demonstrates less inhibition of PI3Kgamma with an IC50 of 0.59 µM. Target: mTOR, PI3K, DNA-PK. Smiles: CCN1CCN(CC(=O)Nc2ccc(-c3cccc4c3oc(cc4=O)N3CCOCC3)c3sc4ccccc4c23)CC1. References: Munck JM, et al. Mol Cancer Ther, 2012, 11(8), 1789-1798.
| Keywords: | KU0060648 |
| Supplier: | TargetMol |
| Supplier-Nr: | T6557 |
Properties
| Application: | Dual PI3K & DNA-PK inhibitor |
| MW: | 582.71 D |
| Formula: | C33H34N4O4S |
Database Information
| CAS : | 881375-00-4| Matching products |
| KEGG ID : | K06642 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301 |
| P Phrases: | P264, P270, P321, P330, P301+P310, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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