Kobe0065
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Kobe0065 is a novel and effective small-molecule compound that inhibits the Ras-Raf... more
Product information "Kobe0065"
Description: Kobe0065 is a novel and effective small-molecule compound that inhibits the Ras-Raf interaction by structure-based drug design (SBDD), it displays potent activity, competitively inhibiting the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 µM. Target: Raf, Apoptosis, Ras. Smiles: Cc1ccc(NC(=S)NNc2c(cc(cc2[N+]([O-])=O)C(F)(F)F)[N+]([O-])=O)cc1Cl. References: Shima F, et al. Proc Natl Acad Sci U S A. 2013, 110(20):8182-7.
| Supplier: | TargetMol |
| Supplier-Nr: | T1876 |
Properties
| Application: | Ras inhibitor |
| MW: | 449.79 D |
| Formula: | C15H11ClF3N5O4S |
Database Information
| CAS : | 436133-68-5| Matching products |
| KEGG ID : | K02833 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
Viewed