KMH-233

Item number	Size	Delivery time	Price
TGM-T32404-25mg	25 mg	7 - 10 business days*	1,530.00€
TGM-T32404-50mg	50 mg	7 - 10 business days*	1,991.00€
TGM-T32404-100mg	100 mg	7 - 10 business days*	2,984.00€

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Description: KMH-233 is a potent selective LAT1 inhibitor 1 that inhibits the uptake of LAT1... more

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Product information "KMH-233"

Description: KMH-233 is a potent selective LAT1 inhibitor 1 that inhibits the uptake of LAT1 substrate, L-leucine, and cell growth. Even at low concentrations (25 µM), it significantly enhanced the efficacy of betastatin and cisplatin. Target: Others. Smiles: CNC(=O)COc1ccc(cc1)-c1c(C#N)c(NC(=O)c2cccc(C[C@H](N)C(O)=O)c2)n2c3ccccc3nc2c1C#N. References: A Selective and Slowly Reversible Inhibitor of l-Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells Kristiina M. Huttunen, Mikko Gynther, Johanna Huttunen, Elena Puris, Julie A. Spicer, and William A. Denny Publication Date (Web): June 2, 2016 (Article) doi: 10.1021/acs.jmedchem.6b00190

Keywords:	KMH233
Supplier:	TargetMol
Supplier-Nr:	T32404

Properties

Application:	LAT1 inhibitor
MW:	587.58 D
Formula:	C32H25N7O5

Database Information

CAS :	1941174-13-5\| Matching products
KEGG ID :	K13780 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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