Kaempferol 7-O-glucoside

Kaempferol 7-O-glucoside is a flavonol glycoside that has been found in C. tricuspidata and A. pilosa and has diverse biological activities. It scavenges DPPH (Cay-14805) radicals (IC50 = 51.09 µM) and inhibits acetylcholinesterase (AChE) activity (IC50 = 63.94 µM) in cell-free assays. Kaempferol 7-O-glucoside inhibits LPS-induced IL-1beta, IL-6, and TNF-alpha production in mouse RAW 264.7 macrophages in a concentration-dependent manner. It also inhibits the proliferation of human HeLa cervical, K562 leukemia, and A431 epidermoid carcinoma cells (EC50s = 3.9, 3.9, and 14.8 µg/ml, respectively).Formal Name: 7-(beta-D-glucopyranosyloxy)-3,5-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. CAS Number: 16290-07-6. Synonyms: Kaempferol 7-O-beta-d-glucoside. Molecular Formula: C21H20O11. Formula Weight: 448.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 229, 256, 268, 368 nm. SMILES: O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)C=C2OC(C4=CC=C(C=C4)O)=C1O. InChi Code: InChI=1S/C21H20O11/c22-7-13-15(25)17(27)19(29)21(32-13)30-10-5-11(24)14-12(6-10)31-20(18(28)16(14)26)8-1-3-9(23)4-2-8/h1-6,13,15,17,19,21-25,27-29H,7H2/t13-,15-,17+,19-,21-/m1/s1. InChi Key: YPWHZCPMOQGCDQ-HMGRVEAOSA-N. Origin: Plant/Ginkgo biloba.