K777

K777
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T15641-1mg 1 mg

7 - 10 business days*

79.00€
TGM-T15641-5mg 5 mg

7 - 10 business days*

189.00€
TGM-T15641-10mg 10 mg

7 - 10 business days*

296.00€
TGM-T15641-1mL 1 ml

7 - 10 business days*

445.00€
TGM-T15641-25mg 25 mg

7 - 10 business days*

505.00€
TGM-T15641-50mg 50 mg

7 - 10 business days*

742.00€
 
Description: K777 is a potent, orally active, and irreversible inhibitor of cysteine protease,... more
Product information "K777"
Description: K777 is a potent, orally active, and irreversible inhibitor of cysteine protease, functioning as a potent CYP3A4 inhibitor (IC50 = 60 nM) and a selective CCR4 antagonist, which inhibits chemotaxis. K777 irreversibly inhibits Cruzain, the major cysteine protease of Trypanosoma cruzi, and cathepsins B and L, targeting cathepsin-mediated cell entry and exhibiting broad-spectrum antiviral activity. It inhibits EBOV and SARS-CoV pseudovirus entry with IC50 values of 0.87 nM and 0.68 nM, respectively. Target: CCR, Cysteine Protease, P450. Smiles: CN1CCN(CC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCc1ccccc1)\C=C\S(=O)(=O)c1ccccc1. References: Zhou Y, et al. Protease inhibitors targeting coronavirus and filovirus entry. Antiviral Res. 2015 Apr,116:76-84.
Keywords: APC-3316
Supplier: TargetMol
Supplier-Nr: T15641

Properties

MW: 574.73 D
Formula: C32H38N4O4S

Database Information

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "K777"
Write a review
or to review a product.
Viewed