Josamycin Solution (in acetone)

Josamycin Solution (in acetone)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CDX-J0009-L001 1 ml - -

3 - 9 business days*

91.00€
CDX-J0009-L005 5 ml - -

3 - 9 business days*

274.00€
 
Liquid. Soluble in water. Chemical. CAS: 16846-24-5. Formula: C42H69NO15. MW: 827.99. Josamycin... more
Product information "Josamycin Solution (in acetone)"
Liquid. Soluble in water. Chemical. CAS: 16846-24-5. Formula: C42H69NO15. MW: 827.99. Josamycin is a member of the leucomycin family of macrolide antibiotics produced by Streptomyces kitasatoensis. It is an antimicrobial against a wide variety of pathogens. It has activity against Gram-positive an Gram-negative bacteria. The mechanism of action is via inhibition of bacterial protein biosynthesis by binding reversibly to the subunit 50S of the bacterial ribosome, inhibiting peptidyltransferase and ribosomal translocation, thereby inhibiting translocation of peptidyl tRNA. Josamycin may overcome anticancer drug resistance by inhibiting the binding of vinblastine or cyclosporin A to P-glycoprotein (Pgp). It is used to study the modification of phagocytosis and cytokine production by macrolide antibiotics and immunomodulatory effects.
Keywords: Kitasamycin A3, Leucomycin A3, Turimycin A5
Supplier: Chemodex
Supplier-Nr: J0009

Properties

Host: Microbial
MW: 827,99 D
Formula: C42H69NO15
Purity: > 98% (UV)
Format: Liquid

Database Information

CAS : 16846-24-5| Matching products

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336
P Phrases: P210, P305+P351+P338, P370+P378, P403+P235
Caution
Our products are for laboratory research use only: Not for administration to humans!
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