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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CDX-J0009-L001 | 1 ml | - | - |
3 - 9 business days* |
91.00€
|
||
CDX-J0009-L005 | 5 ml | - | - |
3 - 9 business days* |
274.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Liquid. Soluble in water. Chemical. CAS: 16846-24-5. Formula: C42H69NO15. MW: 827.99. Josamycin... more
Product information "Josamycin Solution (in acetone)"
Liquid. Soluble in water. Chemical. CAS: 16846-24-5. Formula: C42H69NO15. MW: 827.99. Josamycin is a member of the leucomycin family of macrolide antibiotics produced by Streptomyces kitasatoensis. It is an antimicrobial against a wide variety of pathogens. It has activity against Gram-positive an Gram-negative bacteria. The mechanism of action is via inhibition of bacterial protein biosynthesis by binding reversibly to the subunit 50S of the bacterial ribosome, inhibiting peptidyltransferase and ribosomal translocation, thereby inhibiting translocation of peptidyl tRNA. Josamycin may overcome anticancer drug resistance by inhibiting the binding of vinblastine or cyclosporin A to P-glycoprotein (Pgp). It is used to study the modification of phagocytosis and cytokine production by macrolide antibiotics and immunomodulatory effects.
Keywords: | Kitasamycin A3, Leucomycin A3, Turimycin A5 |
Supplier: | Chemodex |
Supplier-Nr: | J0009 |
Properties
Host: | Microbial |
MW: | 827,99 D |
Formula: | C42H69NO15 |
Purity: | > 98% (UV) |
Format: | Liquid |
Database Information
CAS : | 16846-24-5| Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +20°C (International: +20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
|
H Phrases: | H225, H319, H336 |
P Phrases: | P210, P305+P351+P338, P370+P378, P403+P235 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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