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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay29231-500 | 500 µg | - |
6 - 10 business days* |
145.00€
|
|||
| Cay29231-1 | 1 mg | - |
6 - 10 business days* |
271.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
JNJ-64619178 is an inhibitor of protein arginine methyltransferase 5 (PRMT5, IC50 = 0.14 nM). It... more
Product information "JNJ-64619178"
JNJ-64619178 is an inhibitor of protein arginine methyltransferase 5 (PRMT5, IC50 = 0.14 nM). It inhibits the growth of various cancer cells in vitro and reduces tumor growth in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) mouse xenograft models.Formal Name: (1S,2R,3S,5R)-3-[2-(2-amino-3-bromo-7-quinolinyl)ethyl]-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1,2-cyclopentanediol. CAS Number: 2086772-26-9. Molecular Formula: C22H23BrN6O2. Formula Weight: 483.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 214, 233 nm. SMILES: O[C@H]1[C@@H](O)[C@@](N2C=CC3=C(N)N=CN=C32)([H])C[C@@H]1CCC4=CC=C(C=C(Br)C(N)=N5)C5=C4. InChi Code: InChI=1S/C22H23BrN6O2/c23-15-8-12-3-1-11(7-16(12)28-21(15)25)2-4-13-9-17(19(31)18(13)30)29-6-5-14-20(24)26-10-27-22(14)29/h1,3,5-8,10,13,17-19,30-31H,2,4,9H2,(H2,25,28)(H2,24,26,27)/t13-,17+,18+,19-/m0/s1. InChi Key: DBSMLQTUDJVICQ-CJODITQLSA-N.
| Keywords: | (1S,2R,3S,5R)-3-[2-(2-amino-3-bromo-7-quinolinyl)ethyl]-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1,2-cyclopentanediol |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 29231 |
Properties
| Application: | PRMT5 inhibitor |
| MW: | 483.4 D |
| Formula: | C22H23BrN6O2 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 2086772-26-9| Matching products |
| KEGG ID : | K02516 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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