JNJ-10198409

Item number	Size	Delivery time	Price
TGM-T15616-1mg	1 mg	7 - 10 business days*	30.00€
TGM-T15616-5mg	5 mg	7 - 10 business days*	88.00€
TGM-T15616-1mL	1 ml	7 - 10 business days*	105.00€
TGM-T15616-10mg	10 mg	7 - 10 business days*	130.00€
TGM-T15616-25mg	25 mg	7 - 10 business days*	219.00€
TGM-T15616-50mg	50 mg	7 - 10 business days*	323.00€
TGM-T15616-100mg	100 mg	7 - 10 business days*	464.00€

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Description: JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor... more

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Product information "JNJ-10198409"

Description: JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-beta kinase (IC50=4.2 nM) and PDGFR-alpha kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. Target: PDGFR. Smiles: COc1cc2Cc3c(Nc4cccc(F)c4)n[nH]c3-c2cc1OC. References: D'Andrea MR, et al. Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis. Mol Cancer Ther. 2005 Aug,4(8):1198-204.

Keywords:	JNJ-10198409
Supplier:	TargetMol
Supplier-Nr:	T15616

Properties

Application:	PDGF-BB inhibitor
MW:	325.34 D
Formula:	C18H16FN3O2

Database Information

CAS :	627518-40-5\| Matching products
KEGG ID :	K05089 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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