JNJ-10198409

JNJ-10198409
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T15616-1mg 1 mg

7 - 10 business days*

30.00€
TGM-T15616-5mg 5 mg

7 - 10 business days*

88.00€
TGM-T15616-1mL 1 ml

7 - 10 business days*

105.00€
TGM-T15616-10mg 10 mg

7 - 10 business days*

130.00€
TGM-T15616-25mg 25 mg

7 - 10 business days*

219.00€
TGM-T15616-50mg 50 mg

7 - 10 business days*

323.00€
TGM-T15616-100mg 100 mg

7 - 10 business days*

464.00€
 
Description: JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor... more
Product information "JNJ-10198409"
Description: JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-beta kinase (IC50=4.2 nM) and PDGFR-alpha kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. Target: PDGFR. Smiles: COc1cc2Cc3c(Nc4cccc(F)c4)n[nH]c3-c2cc1OC. References: D'Andrea MR, et al. Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis. Mol Cancer Ther. 2005 Aug,4(8):1198-204.
Keywords: JNJ-10198409
Supplier: TargetMol
Supplier-Nr: T15616

Properties

Application: PDGF-BB inhibitor
MW: 325.34 D
Formula: C18H16FN3O2

Database Information

CAS : 627518-40-5| Matching products
KEGG ID : K05089 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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