Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay30784-1 | 1 mg | - |
6 - 10 business days* |
77.00€
|
|||
| Cay30784-5 | 5 mg | - |
6 - 10 business days* |
312.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4... more
Product information "JKE-1674"
JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4 inhibitor ML-210 (Cay-23282). JKE-1674 reduces viability of LOX-IMVI cancer cells (EC50 = 0.03 µM) and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 (Cay-17729).Formal Name: (E)-1-(4-(bis(4-chlorophenyl)methyl)piperazin-1-yl)-2-(hydroxyimino)-3-nitropropan-1-one. CAS Number: 2421119-60-8. Molecular Formula: C20H20Cl2N4O4. Formula Weight: 451.3. Purity: >98% (mixture of isomers). Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: soluble. lambdamax: 232 nm. SMILES: O=C(C(C[N+]([O-])=O)=NO)N1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)CC1. InChi Code: InChI=1S/C20H20Cl2N4O4/c21-16-5-1-14(2-6-16)19(15-3-7-17(22)8-4-15)24-9-11-25(12-10-24)20(27)18(23-28)13-26(29)30/h1-8,19,28H,9-13H2/b23-18+. InChi Key: XIOHKIAPXVDWCP-PTGBLXJZSA-N.
| Keywords: | (E)-1-(4-(bis(4-chlorophenyl)methyl)piperazin-1-yl)-2-(hydroxyimino)-3-nitropropan-1-one |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 30784 |
Properties
| Application: | Glutathione peroxidase 4 (GPX4) inhibitor |
| MW: | 451.3 D |
| Formula: | C20H20Cl2N4O4 |
| Purity: | >98% (mixture of isomers) |
| Format: | Crystalline Solid |
Database Information
| CAS : | 2421119-60-8| Matching products |
| KEGG ID : | K05361 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed