JK-P3
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 µM). JK-P3 inhibits FGFR... more
Product information "JK-P3"
Description: JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 µM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation. Target: VEGFR. Smiles: COc1ccc(cc1OC)C(=O)Nc1cc([nH]n1)-c1ccccc1. References: Antony M. Latham, et al. Identification of Receptor Tyrosine Kinase Inhibitors Using Cell Surface Biotinylation and Affinity Isolation. VEGF Signaling pp 121-131 , Cite as
| Supplier: | TargetMol |
| Supplier-Nr: | T4425 |
Properties
| Application: | VEGFR2 inhibitor |
| MW: | 323.35 D |
| Formula: | C18H17N3O3 |
Database Information
| CAS : | 942655-44-9| Matching products |
| KEGG ID : | K05098 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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