JH-II-127

Item number	Size	Delivery time	Price
TGM-T7155-1mg	1 mg	7 - 10 business days*	45.00€
TGM-T7155-5mg	5 mg	7 - 10 business days*	105.00€
TGM-T7155-1mL	1 ml	7 - 10 business days*	117.00€
TGM-T7155-10mg	10 mg	7 - 10 business days*	172.00€
TGM-T7155-25mg	25 mg	7 - 10 business days*	295.00€
TGM-T7155-50mg	50 mg	7 - 10 business days*	478.00€
TGM-T7155-100mg	100 mg	7 - 10 business days*	679.00€

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Description: JH-II-127 is an oral inhibitor of leucine-rich repeat kinase 2 (LRRK2), targeting WT... more

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Product information "JH-II-127"

Description: JH-II-127 is an oral inhibitor of leucine-rich repeat kinase 2 (LRRK2), targeting WT LRRK2, G2019S LRRK2, and A2016T LRRK2 with IC50 values of 6.6 nM, 2.2 nM, and 47.7 nM, respectively. Target: LRRK2. Smiles: CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]cc(Cl)c12. References: Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor[J]. ACS Medicinal Chemistry Letters, 2015, 6(5):584-589.

Supplier:	TargetMol
Supplier-Nr:	T7155

Properties

Application:	LRRK2 inhibitor
MW:	416.86 D
Formula:	C19H21ClN6O3

Database Information

CAS :	1700693-08-8\| Matching products
KEGG ID :	K08844 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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