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JC2-11

TargetMol
JC2-11
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T77579-1mg 1 mg -

7 - 10 business days*

38.00€
TGM-T77579-5mg 5 mg -

7 - 10 business days*

87.00€
TGM-T77579-1mL 1 ml -

7 - 10 business days*

96.00€
TGM-T77579-10mg 10 mg -

7 - 10 business days*

144.00€
TGM-T77579-25mg 25 mg -

7 - 10 business days*

285.00€
TGM-T77579-50mg 50 mg -

7 - 10 business days*

478.00€
TGM-T77579-100mg 100 mg -

7 - 10 business days*

697.00€
TGM-T77579-500mg 500 mg -

7 - 10 business days*

1,452.00€
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
 
Description Product Citations Certificate of Analysis Reviews 0
Description
Description: JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment... more
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Product information "JC2-11"
Description: JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen species (ROS) production and caspase-1 activity.JC2-11 reduces caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1beta and lactate dehydrogenase (LDH) activity in inflammatory vesicles. JC2-11 reduced caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1beta and lactate dehydrogenase (LDH) release from inflammatory vesicles. Target: IL Receptor, AIM2, ROS, Dehydrogenase, NOD-like Receptor (NLR), Caspase. Smiles: C(/C=C/C1=CC(OC)=C(O)C=C1)(=O)C2=CC(F)=C(OC)C=C2. References: Lee G, et al. JC2-11, a benzylideneacetophenone derivative, attenuates inflammasome activation. Sci Rep. 2022,12(1):22484.
Supplier: TargetMol
Supplier-Nr: T77579

Properties

MW: 302.3 D
Formula: C17H15FO4

Database Information

CAS : 937820-89-8| Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Product Citations
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