Ixazomib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Ixazomib (MLN2238) , a second generation, boron-containing peptide proteasome... more
Product information "Ixazomib"
Description: Ixazomib (MLN2238) , a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (beta5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also inhibits the caspase-like (beta1) and trypsin-like (beta2) proteolytic sites (IC50: 31/3500 nM). Target: Proteasome, Autophagy, Caspase. Smiles: CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B(O)O. References: Kupperman E, et al. Cancer Res, 2010, 70(5), 1970-80
| Keywords: | MLN2238 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2122 |
Properties
| Application: | Targets 20S proteasome subunit beta 5 [EC:3.4.25.1] (PSMB5) |
| MW: | 361.03 D |
| Formula: | C14H19BCl2N2O4 |
Database Information
| CAS : | 1072833-77-2| Matching products |
| KEGG ID : | K02737 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H360, H362 |
| P Phrases: | P201, P202, P260, P263, P264, P270, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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