Ixazomib citrate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Ixazomib citrate (MLN9708) is a prodrug of Ixazomib (MLN-2238) and an orally... more
Product information "Ixazomib citrate"
Description: Ixazomib citrate (MLN9708) is a prodrug of Ixazomib (MLN-2238) and an orally bioavailable second-generation proteasome inhibitor with an IC50 of 3.4 nM, exhibiting potential antineoplastic activity. Target: Proteasome, Autophagy. Smiles: CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B1OC(=O)C(CC(O)=O)(CC(O)=O)O1. References: Chauhan D, et al. In vitro and in vivo selective antitumor activity of a novel orally bioavailable proteasome inhibitor MLN9708 against multiple myeloma cells. Clin Cancer Res. 2011 Aug 15,17(16):5311-21.
| Keywords: | MLN9708 |
| Supplier: | TargetMol |
| Supplier-Nr: | T8397 |
Properties
| Application: | Targets 20S proteasome subunit beta 5 [EC:3.4.25.1] (PSMB5) |
| MW: | 517.12 D |
| Formula: | C20H23BCl2N2O9 |
Database Information
| CAS : | 1239908-20-3| Matching products |
| KEGG ID : | K02737 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H360, H362 |
| P Phrases: | P201, P202, P260, P263, P264, P270, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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