Ivermectin B1b

Ivermectin B1b
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay23824-500 500 µg -

6 - 10 business days*

417.00€
Cay23824-2.5 2500 µg -

6 - 10 business days*

1,761.00€
 
Ivermectin B1b is the minor component (1a (>80%, Cay-18768). It produces antiparasitic activity... more
Product information "Ivermectin B1b"
Ivermectin B1b is the minor component (1a (>80%, Cay-18768). It produces antiparasitic activity by binding to glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells, inducing irreversible channel opening and very long-lasting hyperpolarization/depolarization of the neuron/muscle cell, thereby blocking further function. Formulations containing ivermectin inhibit replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Vero/hSLAM cells.Formal Name: 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-avermectin A1a. CAS Number: 70209-81-3. Synonyms: 22,23-dihydro Avermectin B1b. Molecular Formula: C47H72O14. Formula Weight: 861.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: Soluble, DMSO: Soluble, Ethanol: Soluble, Methanol: Soluble. SMILES: C/C([C@@H](O[C@@]1([H])C[C@H](OC)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)O1)[C@@H](C)/C=C/C=C(CO3)/[C@@]([C@@]3([H])[C@H](O)C(C)=C4)(O)[C@]4([H])C5=O)=C\C[C@]6([H])C[C@@](O5)([H])C[C@]7(CC[C@H](C)[C@](C(C)C)([H])O7)O6. InChi Code: InChI=1S/C47H72O14/c1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h11-14,18,24-25,27,29-30,32-44,48-49,51H,15-17,19-23H2,1-10H3/b12-11+,26-14+,31-13+/t25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46+,47+/m0/s1. InChi Key: VARHUCVRRNANBD-PVVXTEPVSA-N.
Keywords: 22,23-dihydro Avermectin B1b, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-avermectin A1a
Supplier: Cayman Chemical
Supplier-Nr: 23824

Properties

Application: Anthelmintic, Glutamate-gated chloride channel opener
MW: 861.1 D
Formula: C47H72O14
Purity: >95%
Format: Solid

Database Information

CAS : 70209-81-3| Matching products
KEGG ID : K05273 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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