Isoprinosine

Isoprinosine is a complex of acetaminobenzoic acid, dimethylaminoisopropanol, and inosine in a 3:3:1 ratio. It has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects and others, isoprinosine shows antiviral activity and has applications against subacute sclerosing panencephalitis. It also restores depressed immune responses in cancer patients after irradiation and reduces the incidence of infection in leukemia patients undergoing chemotherapy.Formal Name: 1-(dimethylamino)-2-propanol 4-(acetylamino)benzoate inosine. CAS Number: 36703-88-5. Synonyms: Inosine pranobex, NP 113, NPT 10381. Molecular Formula: C10H12N4O5 . 3C9H9NO3 . 3C5H13NO. Formula Weight: 1115.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 14 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 259 nm. SMILES: OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2NC=NC3=O)O1.OC(C4=CC=C(NC(C)=O)C=C4)=O.CC(O)CN(C)C.OC(C5=CC=C(NC(C)=O)C=C5)=O.CC(O)CN(C)C.OC(C6=CC=C(NC(C)=O)C=C6)=O.CC(O)CN(C)C. InChi Code: InChI=1S/C10H12N4O5.3C9H9NO3.3C5H13NO/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18,3*1-6(11)10-8-4-2-7(3-5-8)9(12)13,3*1-5(7)4-6(2)3/h2-4,6-7,10,15-17H,1H2,(H,11,12,18),3*2-5H,1H3,(H,10,11)(H,12,13),3*5,7H,4H2,1-3H3/t4-,6-,7-,10-,,,,,,/m1.. InChi Key: YLDCUKJMEKGGFI-QCSRICIXSA-N.