Infigratinib

Item number	Size	Delivery time	Price
TGM-T1975-5mg	5 mg	7 - 10 business days*	41.00€
TGM-T1975-1mL	1 ml	7 - 10 business days*	45.00€
TGM-T1975-10mg	10 mg	7 - 10 business days*	55.00€
TGM-T1975-25mg	25 mg	7 - 10 business days*	83.00€
TGM-T1975-50mg	50 mg	7 - 10 business days*	97.00€
TGM-T1975-100mg	100 mg	7 - 10 business days*	157.00€
TGM-T1975-200mg	200 mg	7 - 10 business days*	287.00€
TGM-T1975-500mg	500 mg	7 - 10 business days*	494.00€

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Description: Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor... more

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Product information "Infigratinib"

Description: Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2. Target: Apoptosis, FGFR. Smiles: CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)cc1. References: Guagnano V, et al. Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase. J Med Chem. 2011 Oct 27,54(20):7066-83.

Keywords:	BGJ-398, NVP-BGJ398
Supplier:	TargetMol
Supplier-Nr:	T1975

Properties

Application:	Targets fibroblast growth factor receptor 1 [EC:2.7.10.1] (FGFR1, CD331)
MW:	560.48 D
Formula:	C26H31Cl2N7O3

Database Information

CAS :	872511-34-7\| Matching products
KEGG ID :	K04362 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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