Incensole

Incensole is a diterpene originally isolated from frankincense produced by B. carterii. It inhibits degradation of inhibitor of NF-kappaB (IkappaBalpha) in a concentration-dependent manner in TNF-alpha-stimulated HeLa cells when used at concentrations ranging from 60 to 140 µM.Formal Name: (1R,2S,5E,9E,12S)-1,5,9-trimethyl-12-(1-methylethyl)-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol. CAS Number: 22419-74-5. Molecular Formula: C20H34O2. Formula Weight: 306.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml. SMILES: C/C1=C/CC/C(C)=C/C[C@@](C(C)C)(O2)CC[C@]2(C)[C@@H](O)CC1. InChi Code: InChI=1S/C20H34O2/c1-15(2)20-12-11-17(4)8-6-7-16(3)9-10-18(21)19(5,22-20)13-14-20/h7,11,15,18,21H,6,8-10,12-14H2,1-5H3/b16-7-,17-11+/t18-,19+,20+/m0/s1. InChi Key: SSBZLMMXFQMHDP-LRQRMEBUSA-N.