Imatinib Mesylate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with... more
Product information "Imatinib Mesylate"
Description: Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 µM, 0.1 µM and 0.1 µM for v-Abl, c-Kit and PDGFR, respectively). Target: Bcr-Abl, Autophagy, PDGFR, c-Kit. Smiles: CS(O)(=O)=O.CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1. References: Gobin B, et al. Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models. PLoS One. 2014 Mar 5,9(3):e90795.
| Keywords: | ST-1571 Mesylate, CGP-57148B, STI-571 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1621 |
Properties
| Application: | Targets abelson tyrosine-protein kinase 1 [EC:2.7.10.2] (ABL1) |
| MW: | 589.71 D |
| Formula: | C29H31N7O·CH4SO3 |
Database Information
| CAS : | 220127-57-1| Matching products |
| KEGG ID : | K04363 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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