Iguratimod
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Iguratimod (T614) is an antirheumatic agent, acts as an inhibitor of COX-2, with an... more
Product information "Iguratimod"
Description: Iguratimod (T614) is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 µM (7.7 µg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migration inhibitory factor (MIF) with an IC50 of 6.81 µM. Target: COX, Others. Smiles: O=C1C=2C(=CC(NS(C)(=O)=O)=C(OC3=CC=CC=C3)C2)OC=C1NC=O. References: Tanaka K, et al. T-614, a novel antirheumatic drug, inhibits both the activity and induction of cyclooxygenase-2 (COX-2) in cultured fibroblasts. Jpn J Pharmacol. 1995 Apr,67(4):305-14.
| Keywords: | T614 |
| Supplier: | TargetMol |
| Supplier-Nr: | T5032 |
Properties
| Application: | Targets nuclear factor NF-kappa-B p105 subunit (NFKB1) |
| MW: | 374.37 D |
| Formula: | C17H14N2O6S |
Database Information
| CAS : | 123663-49-0| Matching products |
| KEGG ID : | K02580 | Matching products |
| Protein Atlas Nr. : | Gene Regulation |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H361 |
| P Phrases: | P201, P202, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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