IDO-IN-3

IDO-IN-3 is an inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1, IC50s = 290 and 98 nM for the human recombinant enzyme in a cell-free assay and in HeLa cells, respectively).Formal Name: 4-[(2-aminoethyl)amino]-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide. CAS Number: 2070018-30-1. Molecular Formula: C11H12BrFN6O2. Formula Weight: 359.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Ethanol: 1 mg/ml. lambdamax: 211, 290 nm. SMILES: BrC1=C(F)C=CC(/N=C(C2=NON=C2NCCN)/NO)=C1. InChi Code: InChI=1S/C11H12BrFN6O2/c12-7-5-6(1-2-8(7)13)16-11(17-20)9-10(15-4-3-14)19-21-18-9/h1-2,5,20H,3-4,14H2,(H,15,19)(H,16,17). InChi Key: DAPNMIADTFAXEG-UHFFFAOYSA-N.