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Description: IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 values of 59 nM for human IDO enzymatic activity and 12 nM for HeLa cell assays. Target: Indoleamine 2,3-Dioxygenase (IDO). Smiles: Nc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O. References: Discovery of Potent Competitive Inhibitors of Indoleamine 2,3-Dioxygenase with in Vivo Pharmacodynamic Activity and Efficacy in a Mouse Melanoma Model[J]. Journal of Medicinal Chemistry, 2009, 52(23):7364-7367.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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