iCRT 14
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: iCRT 14 is a novel and potent inhibitor of beta-catenin-responsive transcription... more
Product information "iCRT 14"
Description: iCRT 14 is a novel and potent inhibitor of beta-catenin-responsive transcription (CRT) with an IC50 of 40.3 nM in assays of Wnt pathway activity. Target: Wnt/beta-catenin. Smiles: Cc1cc(C=C2SC(=O)N(C2=O)c2ccccc2)c(C)n1-c1cccnc1. References: Gonsalves FC, et al. An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway. Proc Natl Acad Sci USA. 2011 Apr 12,108(15):5954-63.
| Supplier: | TargetMol |
| Supplier-Nr: | T4486 |
Properties
| Application: | beta-catenin inhibitor |
| MW: | 375.44 D |
| Formula: | C21H17N3O2S |
Database Information
| CAS : | 677331-12-3| Matching products |
| KEGG ID : | K02105 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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