ICA-121431
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small... more
Product information "ICA-121431"
Description: ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1.7 channels. Target: Sodium Channel. Smiles: O=C(Nc1ccc(cc1)S(=O)(=O)Nc1nccs1)C(c1ccccc1)c1ccccc1. References: Song G , Yang D , Wang Y , et al. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators[J]. Nature, 2017.
| Keywords: | 2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl |
| Supplier: | TargetMol |
| Supplier-Nr: | T7336 |
Properties
| Application: | Voltage-gated sodium channel (Nav) blocker |
| MW: | 449.55 D |
| Formula: | C23H19N3O3S2 |
Database Information
| CAS : | 313254-51-2| Matching products |
| KEGG ID : | K04836 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H302, H319, H413 |
| P Phrases: | P264, P270, P273, P280, P301+310, P305+351+338, P330, P337+313, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
Viewed