Hydroxy Pioglitazone

Hydroxy Pioglitazone
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay28043-1 1 mg -

6 - 10 business days*

369.00€
Cay28043-5 5 mg -

6 - 10 business days*

1,098.00€
 
Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor... more
Product information "Hydroxy Pioglitazone"
Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor gamma (PPARgamma) agonist pioglitazone (Cay-71745, Cay-22263, Cay-10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to PPARgamma (Ki = 1.2 µM) and activates PPARgamma in a time-resolved FRET (TR-FRET) assay (EC50 = 2.1 µM).Formal Name: 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione. CAS Number: 146062-44-4. Molecular Formula: C19H20N2O4S. Formula Weight: 372.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: soluble, DMSO: soluble. SMILES: CC(O)C1=CN=C(CCOC2=CC=C(CC3SC(NC3=O)=O)C=C2)C=C1. InChi Code: InChI=1S/C19H20N2O4S/c1-12(22)14-4-5-15(20-11-14)8-9-25-16-6-2-13(3-7-16)10-17-18(23)21-19(24)26-17/h2-7,11-12,17,22H,8-10H2,1H3,(H,21,23,24). InChi Key: OXVFDZYQLGRLCD-UHFFFAOYSA-N.
Keywords: 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione
Supplier: Cayman Chemical
Supplier-Nr: 28043

Properties

Application: Major metabolite
MW: 372.4 D
Formula: C19H20N2O4S
Purity: >95%
Format: Solid

Database Information

CAS : 146062-44-4| Matching products
KEGG ID : K17718 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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