Hydroxy bosentan

Item number	Size	Manual	Delivery time	Price
TGM-T19360-500ug	500 µg	-	7 - 10 business days*	287.00€
TGM-T19360-1mg	1 mg		7 - 10 business days*	541.00€
TGM-T19360-5mg	5 mg		7 - 10 business days*	2,111.00€

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Description: Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized... more

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Product information "Hydroxy bosentan"

Description: Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver, assisting BOS pharmacologically with 10%-20% activity retention. Target: Others. Smiles: O=S(=O)(NC=1N=C(N=C(OCCO)C1OC=2C=CC=CC2OC)C3=NC=CC=N3)C4=CC=C(C=C4)C(C)(C)CO. References: Chen M, et al. Comparison of the inhibitory effect of ketoconazole, voriconazole, fluconazole, and itraconazoleon the pharmacokinetics of bosentan and its corresponding active metabolite hydroxy bosentanin rats. Xenobiotica. 2019 Jul 3:1-8.

Keywords:	Ro 48-5033
Supplier:	TargetMol
Supplier-Nr:	T19360

Properties

MW:	567.61 D
Formula:	C27H29N5O7S

Database Information

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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