Homoharringtonine
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Homoharringtonine (HHT) is a natural alkaloid that inhibits the translation of... more
Product information "Homoharringtonine"
Description: Homoharringtonine (HHT) is a natural alkaloid that inhibits the translation of proteins and is cytotoxic. Homoharringtonine acts on the ribosomes of tumor cells to inhibit the elongation step of protein translation, thereby inhibiting protein synthesis, and has antitumor activity. Target: STAT. Smiles: COC(=O)CC(O)(CCCC(C)(C)O)C(=O)OC1C2c3cc4OCOc4cc3CCN3CCCC23C=C1OC. References: Cao W, et al. Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. Sci Rep. 2015 Jul 13,5:8477.
| Keywords: | Myelostat, HHT, Omacetaxine mepesuccinate, Ceflatonin |
| Supplier: | TargetMol |
| Supplier-Nr: | T3380 |
Properties
| Application: | Targets G1/S-specific cyclin-D1 (CCND1) |
| MW: | 545.62 D |
| Formula: | C29H39NO9 |
Database Information
| CAS : | 26833-87-4| Matching products |
| KEGG ID : | K02539 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H300 |
| P Phrases: | P264, P270, P321, P330, P301+P310, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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