Hexamethylene bisacetamide

Hexamethylene bisacetamide is a tumor cell-differentiating agent. It induces complete differentiation of 754A murine erythroleukemia cells when used at a concentration of 5 mM. Hexamethylene bisacetamide also induces latent HIV-1 viral production in chronically HIV-1-infected U1 cells in a concentration-dependent manner. Implantation of HT-29 colon cancer cells cultured with hexamethylene bisacetamide for seven, but not 28, days reduces tumorigenesis of those cells in mice.Formal Name: N,N'-1,6-hexanediylbis-acetamide. CAS Number: 3073-59-4. Synonyms: HMBA, NSC 95580. Molecular Formula: C10H20N2O2. Formula Weight: 200.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 5 mg/ml, DMSO: 10 mg/ml, Ethanol: 5 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: CC(NCCCCCCNC(C)=O)=O. InChi Code: InChI=1S/C10H20N2O2/c1-9(13)11-7-5-3-4-6-8-12-10(2)14/h3-8H2,1-2H3,(H,11,13)(H,12,14). InChi Key: BNQSTAOJRULKNX-UHFFFAOYSA-N.