HAT Inhibitor II

HAT Inhibitor II is a cell-permeable, selective inhibitor of the histone acetyltransferase p300 (IC50 = 5 µM). It does not inhibit PCAF or GCN5 acetyltransferases.Formal Name: 2,6-bis[(3-bromo-4-hydroxyphenyl)methylene]-cyclohexanone. CAS Number: 932749-62-7. Synonyms: Histone Acetyltransferase Inhibitor II. Molecular Formula: C20H16Br2O3. Formula Weight: 464.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMF:PBS (pH 7.2) (1:8): 0.1 mg/ml, DMSO: 30 mg/ml, Ethanol: 20 mg/ml. lambdamax: 249, 366 nm. SMILES: BrC1=C(O)C=CC(/C=C2CCC/C(C\2=O)=C\C3=CC(Br)=C(O)C=C3)=C1. InChi Code: InChI=1S/C20H16Br2O3/c21-16-10-12(4-6-18(16)23)8-14-2-1-3-15(20(14)25)9-13-5-7-19(24)17(22)11-13/h4-11,23-24H,1-3H2/b14-8+,15-9+. InChi Key: YOLKEKNTCBWPSD-VOMDNODZSA-N.