Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay26116-500 | 500 µg | - |
6 - 10 business days* |
166.00€
|
|||
Cay26116-1 | 1 mg | - |
6 - 10 business days* |
314.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Haloperidol-d4 is intended for use as an internal standard for the quantification of haloperidol... more
Product information "Haloperidol-d4"
Haloperidol-d4 is intended for use as an internal standard for the quantification of haloperidol (Cay-12014) by GC- or LC-MS. Haloperidol is a typical antipsychotic and dopamine D2-like receptor antagonist (Kis = 0.6, 0.2, and 22 nM, for D2, D3, and D4 receptors, respectively). It also acts as an inverse agonist at dopamine D2 and D3 receptors (IC50s = 0.8 and 0.6 nM, respectively). Haloperidol also binds to alpha1- and alpha2- adrenergic and histamine H1 receptors, as well as the serotonin (5-HT) receptor subtypes 5-HT1D and 5-HT2A (Kds = 17, 600, 260, 40, and 61 nM, respectively). It inhibits stereotypic behavior induced by apomorphine (Cay-16094) and amphetamine in rats (ID50s = 0.532 and 0.101 µmol/kg, respectively). Haloperidol also inhibits apomorphine-induced decreases in prepulse inhibition of the acoustic startle response in rats in a dose-dependent manner. Formulations containing haloperidol have been used in the treatment of schizophrenia and Tourette syndrome.Formal Name: 4-(4-(4-chlorophenyl-2,3,5,6-d4)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one. CAS Number: 1189986-59-1. Molecular Formula: C21H19ClD4FNO2. Formula Weight: 379.9. Purity: >99% deuterated forms (d1-d4). Formulation: (Request formulation change), A solid. Solubility: Chloroform: Slightly Soluble, Methanol: Slightly Soluble. SMILES: OC1(CCN(CCCC(C2=CC=C(F)C=C2)=O)CC1)C3=C([2H])C([2H])=C(Cl)C([2H])=C3[2H]. InChi Code: InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2/i5D,6D,7D,8D. InChi Key: LNEPOXFFQSENCJ-KDWZCNHSSA-N.
Keywords: | 4-(4-(4-chlorophenyl-2,3,5,6-d4)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one |
Supplier: | Cayman Chemical |
Supplier-Nr: | 26116 |
Properties
Application: | Dopamine D2 receptor antagonist, GC-MS, LC-MS, Internal standard |
MW: | 379.9 D |
Formula: | C21H19ClD4FNO2 |
Purity: | >99% deuterated forms (d1-d4) |
Format: | Solid |
Database Information
CAS : | 1189986-59-1| Matching products |
KEGG ID : | K04145 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
|
H Phrases: | H301, H315, H317, H319, H335, H361 |
P Phrases: | P201, P202, P261, P264, P270, P271, P272, P280, P301+310, P302+352, P304+340, P305+351+338, P308+313, P312, P321, P330, P332+313, P333+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed