Gymnemic Acid I

Gymnemic Acid I
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay28495-1 1 mg -

6 - 10 business days*

262.00€
Cay28495-5 5 mg -

6 - 10 business days*

1,171.00€
 
Gymnemic acid I is a triterpene glycoside that has been found in G. sylvestre and has... more
Product information "Gymnemic Acid I"
Gymnemic acid I is a triterpene glycoside that has been found in G. sylvestre and has antihyperglycemic activities. It inhibits glucose-induced phosphorylation of serine 70 on S6 kinase (S6K1) and serine 2448 on mTOR, caspase-3 activity, and apoptosis, as well as increases autophagy in MIN-6 pancreatic beta cells when used at a concentration of 5 µg/ml. Gymnemic acid I has been used as a reference compound to compare the potency of plant-derived sweet taste inhibitors.Formal Name: (3beta,4alpha,16beta,21beta,22alpha)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl-beta-D-glucopyranosiduronic acid. CAS Number: 122168-40-5. Synonyms: (+)-Gymnemic Acid I. Molecular Formula: C43H66O14. Formula Weight: 807.0. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: soluble. SMILES: CC1(C)[C@@H](OC(/C(C)=C/C)=O)[C@H](O)[C@]2(COC(C)=O)[C@@H](O)C[C@@]3(C)[C@]4(C)CC[C@@]5([H])[C@](C)(CO)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O6)CC[C@]5(C)[C@@]4([H])CC=C3[C@]2([H])C1. InChi Code: InChI=1S/C43H66O14/c1-10-21(2)36(53)57-34-33(50)43(20-54-22(3)45)24(17-38(34,4)5)23-11-12-26-39(6)15-14-28(55-37-31(49)29(47)30(48)32(56-37)35(51)52)40(7,19-44)25(39)13-16-41(26,8)42(23,9)18-27(43)46/h10-11,24-34,37,44,46-50H,12-20H2,1-9H3,(H,51,52)/b21-10+/t24-,25+,26+,27-,28-,29-,30-,31+,32-,33-,34-,37+,39-,40-,41+,42+,43-/m0/s1. InChi Key: VEFSVJGWJQPWFS-ZXKKMYOJSA-N. Origin: Plant/Gymnema sylvestre (Retz.) Schult..
Keywords: (+)-Gymnemic Acid I, (3beta,4alpha,16beta,21beta,22alpha)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl-beta-D-glucopyranosiduronic acid
Supplier: Cayman Chemical
Supplier-Nr: 28495

Properties

Application: Antihyperglycemic triterpene glycoside
MW: 807 D
Formula: C43H66O14
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 122168-40-5| Matching products
KEGG ID : K07203 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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