Guanfu base A

Item number	Size	Delivery time	Price
TGM-T8182-1mg	1 mg	7 - 10 business days*	81.00€
TGM-T8182-5mg	5 mg	7 - 10 business days*	192.00€
TGM-T8182-10mg	10 mg	7 - 10 business days*	287.00€
TGM-T8182-25mg	25 mg	7 - 10 business days*	486.00€
TGM-T8182-50mg	50 mg	7 - 10 business days*	698.00€
TGM-T8182-100mg	100 mg	7 - 10 business days*	966.00€

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Description: Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 µM in HLMs, Ki:... more

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Product information "Guanfu base A"

Description: Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 µM in HLMs, Ki: 0.37 µM for rCYP2D6). It also inhibits HERG channel current. Target: HER, Potassium Channel, P450. Smiles: [H][C@@]12CC34CC(=C)[C@]5([H])[C@@H](O)[C@@]3([H])[C@@]36C[C@H](C[C@@](C)(CN1C3[C@@]4(O)[C@@H]5OC(C)=O)[C@@]26[H])OC(C)=O. References: Sun J, et al. Guanfu base A, an antiarrhythmic alkaloid of Aconitum coreanum, Is a CYP2D6 inhibitor of human, monkey, and dog isoforms. Drug Metab Dispos. 2015 May,43(5):713-24.

Keywords:	Guan-fu base A
Supplier:	TargetMol
Supplier-Nr:	T8182

Properties

MW:	429.5 D
Formula:	C24H31NO6

Database Information

CAS :

1394-48-5| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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