Guan-fu base A hydrochloride(1394-48-5 free base)

Description: Guan-fu base A hydrochloride is an antiarrhythmic alkaloid was isolated from Aconitum coreanum. Guanfu base A is hydrochloride a CYP2D6 inhibitor of human, monkey, and dog isoforms. Target: P450. Smiles: Cl.[H][C@@]12C[C@]34CC(=C)[C@]5([H])[C@@H](O)[C@@]3([H])[C@@]36C[C@H](C[C@@](C)(CN1[C@]3([H])[C@@]4(O)[C@@H]5OC(C)=O)[C@@]26[H])OC(C)=O. References: Sun J , Peng Y , Wu H , et al. Guanfu base A, an antiarrhythmic alkaloid of Aconitum coreanum, Is a CYP2D6 inhibitor of human, monkey, and dog isoforms.[J]. Drug metabolism and disposition: the biological fate of chemicals, 2015, 43(5).