GSK3685032

Item number	Size	Delivery time	Price
TGM-T9573-1mg	1 mg	7 - 10 business days*	93.00€
TGM-T9573-5mg	5 mg	7 - 10 business days*	198.00€
TGM-T9573-1mL	1 ml	7 - 10 business days*	209.00€
TGM-T9573-10mg	10 mg	7 - 10 business days*	317.00€
TGM-T9573-25mg	25 mg	7 - 10 business days*	596.00€
TGM-T9573-50mg	50 mg	7 - 10 business days*	850.00€
TGM-T9573-100mg	100 mg	7 - 10 business days*	1,170.00€

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Description: GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM). The... more

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Product information "GSK3685032"

Description: GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM). The inhibitory effect is time-independent and reversible. GSK3685032 induces loss of DNA methylation and transcriptional activation and inhibits cancer cell growth. Target: DNA Methyltransferase. Smiles: CCc1c(C#N)c(SC(C(N)=O)c2ccccc2)nc(N2CCC(N)CC2)c1C#N. References: Pappalardi MB, et al. Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer. 2021,2(10):1002-1017.

Supplier:	TargetMol
Supplier-Nr:	T9573

Properties

MW:	420.53 D
Formula:	C22H24N6OS

Database Information

CAS :

2170137-61-6| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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