GSK2194069
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-T15429-2mg | 2 mg |
7 - 10 business days* |
148.00€
|
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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: GSK2194069 is an active beta-keto reductase (KR)-specific inhibitor of fatty acid... more
Product information "GSK2194069"
Description: GSK2194069 is an active beta-keto reductase (KR)-specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released CoA.GSK2194069 inhibits the proliferation of FAS in cancer cells through the action of acetoacetyl-coenzyme A and NADPH. Target: Others, Fatty Acid Synthase, NADPH. Smiles: O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(cc2)-c2ccc3occc3c2)C1. References: Hardwicke MA, et al. A human fatty acid synthase inhibitor binds beta-ketoacyl reductase in the keto-substrate site. Nat Chem Biol. 2014,10(9):774-779.
| Supplier: | TargetMol |
| Supplier-Nr: | T15429 |
Properties
| Application: | FASN inhibitor |
| MW: | 428.48 D |
| Formula: | C25H24N4O3 |
Database Information
| CAS : | 1332331-08-4| Matching products |
| KEGG ID : | K00665 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301 |
| P Phrases: | P264, P270, P301+310, P321, P330, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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