GSK-J1
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and... more
Product information "GSK-J1"
Description: GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases. Target: Histone Demethylase. Smiles: OC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1. References: Kruidenier L, et al. Nature. 2012, 488(7411), 404-408.
| Keywords: | GSK J1 |
| Supplier: | TargetMol |
| Supplier-Nr: | T6847 |
Properties
| Application: | pan-HDAC inhibitor (HDAC1, 2, 4, 10, 11) |
| MW: | 389.45 D |
| Formula: | C22H23N5O2 |
Database Information
| CAS : | 1373422-53-7| Matching products |
| KEGG ID : | K06067 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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