GSK-F1
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Solid. Soluble in DMSO. GSK-F1 is a potent PI4KA inhibitor. It has better pharmacokinetic... more
Product information "GSK-F1"
Solid. Soluble in DMSO. GSK-F1 is a potent PI4KA inhibitor. It has better pharmacokinetic properties in vivo than to GSK-A1 (SYN-1219). GSK-F1 does not cross the blood-brain barrier. Phosphatidylinositol 4-kinase type III? (PI4KA) is a host factor essential for hepatitis C virus replication and hence is a target for drug development. RNAi studies have shown that PI4KA is a mandatory host factor in HCV replication. Down-regulation of PI4KA appears to be reasonably tolerated by cultured cell models and results.
| Keywords: | 5-(2-Amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide, GSKF1 |
| Supplier: | SYNkinase |
| Supplier-Nr: | 1220 |
Properties
| Application: | Potent PI4KA inhibitor |
| MW: | 603,5 D |
| Formula: | C27H18F5N5O4S |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 1402345-92-9| Matching products |
| KEGG ID : | K00888 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +20°C (International: +20°C) |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H317, H332 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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