GSK-25

Item number	Size	Delivery time	Price
TGM-T4488-1mg	1 mg	7 - 10 business days*	40.00€
TGM-T4488-2mg	2 mg	7 - 10 business days*	55.00€
TGM-T4488-5mg	5 mg	7 - 10 business days*	83.00€
TGM-T4488-1mL	1 ml	7 - 10 business days*	97.00€
TGM-T4488-10mg	10 mg	7 - 10 business days*	119.00€
TGM-T4488-25mg	25 mg	7 - 10 business days*	180.00€
TGM-T4488-50mg	50 mg	7 - 10 business days*	285.00€
TGM-T4488-100mg	100 mg	7 - 10 business days*	477.00€

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Description: GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and... more

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Product information "GSK-25"

Description: GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested). Target: S6 Kinase, mTOR, ROCK. Smiles: CC1=C(C(N=C(N1)c1ccnc(Cl)c1)c1ccc(Cl)cc1F)C(=O)Nc1cc2cn[nH]c2cc1F. References: Sehon CA, et al. Potent, selective and orally bioavailable dihydropyrimidine inhibitors of Rho kinase (ROCK1) as potential therapeutic agents for cardiovascular diseases [J]. J Med Chem. 2008 Nov 13,51(21):6631-4.

Keywords:	GSK25
Supplier:	TargetMol
Supplier-Nr:	T4488

Properties

Application:	ROCK1 inhibitor
MW:	513.33 D
Formula:	C24H16Cl2F2N6O

Database Information

CAS :	874119-56-9\| Matching products
KEGG ID :	K04514 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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