GPX4-IN-5

Item number	Size	Manual	Delivery time	Price
TGM-T77755-1mg	1 mg	-	7 - 10 business days*	62.00€
TGM-T77755-5mg	5 mg	-	7 - 10 business days*	149.00€
TGM-T77755-1mL	1 ml	-	7 - 10 business days*	166.00€
TGM-T77755-10mg	10 mg	-	7 - 10 business days*	237.00€
TGM-T77755-25mg	25 mg	-	7 - 10 business days*	388.00€
TGM-T77755-50mg	50 mg	-	7 - 10 business days*	576.00€
TGM-T77755-100mg	100 mg	-	7 - 10 business days*	835.00€

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Description: GPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 µM) with... more

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Product information "GPX4-IN-5"

Description: GPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 µM) with antitumour activity.GPX4-IN-5 induces ferroptosis and can be used for the prevention and treatment of triple-negative breast cancer (TNBC). Target: GPX. Smiles: O=C(N(C1=CC=C2OCCOC2=C1)C3=CC(OC)=C(F)C(OC)=C3)CCl. References: Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27,66(14):10036-10059.

Supplier:	TargetMol
Supplier-Nr:	T77755

Properties

Application:	Covalent GPX4 inhibitor
MW:	381.78 D
Formula:	C18H17ClFNO5

Database Information

CAS :	2922824-09-5\| Matching products
KEGG ID :	K05361 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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