Gilteritinib

Gilteritinib
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T4409-1mg 1 mg -

7 - 10 business days*

34.00€
TGM-T4409-2mg 2 mg -

7 - 10 business days*

50.00€
TGM-T4409-5mg 5 mg -

7 - 10 business days*

80.00€
TGM-T4409-10mg 10 mg -

7 - 10 business days*

120.00€
TGM-T4409-25mg 25 mg -

7 - 10 business days*

192.00€
TGM-T4409-50mg 50 mg -

7 - 10 business days*

284.00€
TGM-T4409-100mg 100 mg -

7 - 10 business days*

447.00€
TGM-T4409-500mg 500 mg -

7 - 10 business days*

1,039.00€
TGM-T4409-1g 1 g -

7 - 10 business days*

1,402.00€
 
Description: Gilteritinib (ASP2215) is a potent inhibitor of FMS-related tyrosine kinase 3 (FLT3)... more
Product information "Gilteritinib"
Description: Gilteritinib (ASP2215) is a potent inhibitor of FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preclinical studies, gilteritinib demonstrated strong antileukemic and antitumor effects. Gilteritinib is currently in several Phase 3 clinical trials for acute myeloid leukemia. Target: TAM Receptor, c-Kit, FLT. Smiles: CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1. References: Mori M, et al. Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia. Invest New Drugs. 2017 Oct,35(5):556-565.
Keywords: ASP2215
Supplier: TargetMol
Supplier-Nr: T4409

Properties

Application: Targets fms-related tyrosine kinase 3 [EC:2.7.10.1] (FLT3, FLK2, CD135)
MW: 552.71 D
Formula: C29H44N8O3

Database Information

CAS : 1254053-43-4| Matching products
KEGG ID : K05092 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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