GGTI 2418
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
GGTI 2418 is an inhibitor of geranylgeranyl transferase type I (GGTase I, IC50 = 9.5 nM). It is... more
Product information "GGTI 2418"
GGTI 2418 is an inhibitor of geranylgeranyl transferase type I (GGTase I, IC50 = 9.5 nM). It is selective for GGTase I over farnysltransferase (FTase, IC50 = 53,000 nM). GGTI 2418 (100 mg/kg) reduces tumor growth in an MDA-MB-231 breast cancer mouse xenograft model.Formal Name: N-[[(2S)-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxo-2-(phenylmethyl)-1-piperazinyl]carbonyl]-L-leucine. CAS Number: 501010-06-6. Molecular Formula: C23H31N5O4. Formula Weight: 441.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: soluble. SMILES: O=C1[C@H](CC2=CC=CC=C2)N(C(N[C@H](C(O)=O)CC(C)C)=O)CCN1CC3=C(C)N=CN3. InChi Code: InChI=1S/C23H31N5O4/c1-15(2)11-18(22(30)31)26-23(32)28-10-9-27(13-19-16(3)24-14-25-19)21(29)20(28)12-17-7-5-4-6-8-17/h4-8,14-15,18,20H,9-13H2,1-3H3,(H,24,25)(H,26,32)(H,30,31)/t18-,20-/m0/s1. InChi Key: COLCNDRDBCLVOC-ICSRJNTNSA-N.
| Keywords: | N-[[(2S)-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxo-2-(phenylmethyl)-1-piperazinyl]carbonyl]-L-leucine |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 28714 |
Properties
| Application: | GGTase I inhibitor |
| MW: | 441.5 D |
| Formula: | C23H31N5O4 |
| Purity: | >98% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 501010-06-6| Matching products |
| KEGG ID : | K11713 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H317, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P272, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P333+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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