Geranylgeranyl Pyrophosphate (ammonium salt)

Description: Geranylgeranyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway derived directly from farnesyl pyrophosphate and used in the biosynthesis of terpenes and terpenoids.[1] It is also serves as a substrate in the prenylation of a variety of critical intracellular proteins including small GTPases.[2] This post-translational modification is necessary for correct localization of proteins to intracellular membranes for proper functionality and has become a focus of anticancer drug discovery.[3][4]. Target: Others. Smiles: C/C(C)=C\CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/COP(OP(O)(O)=O)(O)=O.N.N.N. References: Vance, D.E. Cholesterol and related derivatives. Biochemistry 2nd ed., 725-748 (1988).