Gemcitabine hydrochloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine... more
Product information "Gemcitabine hydrochloride"
Description: Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis. Target: Autophagy, DNA/RNA Synthesis, Apoptosis, Nucleoside Antimetabolite/Analog. Smiles: Cl.Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)c(=O)n1. References: Amrutkar M, et al. Differential Gemcitabine Sensitivity in Primary Human Pancreatic Cancer Cells and Paired Stellate Cells Is Driven by Heterogenous Drug Uptake and Processing. Cancers (Basel). 2020 Dec 3,12(12):3628.
| Keywords: | LY 188011 hydrochloride, Gemzar, LY188011, Gemcitabine HCl |
| Supplier: | TargetMol |
| Supplier-Nr: | T6069 |
Properties
| Application: | Targets ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] (RRM1) |
| MW: | 299.66 D |
| Formula: | C9H11F2N3O4·HCl |
Database Information
| CAS : | 122111-03-9| Matching products |
| KEGG ID : | K10807 | Matching products |
| Protein Atlas Nr. : | Nucleotides & Co |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H360 |
| P Phrases: | P201, P202, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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