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Description: GAT211 (AZ-4) is a selective and potent cannabinoid 1 receptor (CB1R) orthosteric modulator (PAM) with high affinity for cAMP and beta-arrestin2.GAT211 has IOP-lowering and antipsychotic effects and can be used in the study of epilepsy. Target: Cannabinoid Receptor, cAMP, Arrestin. Smiles: [O-][N+](=O)CC(c1c([nH]c2ccccc12)-c1ccccc1)c1ccccc1. References: Garai S, et al. Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure. Bioorg Med Chem. 2021 Nov 15,50:116421.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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