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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay15585-1 | 1 mg | - |
6 - 10 business days* |
77.00€
|
|||
Cay15585-5 | 5 mg | - |
6 - 10 business days* |
351.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone... more
Product information "Ganglioside GD1a (bovine brain) (sodium salt)"
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 µM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin. This product contains ganglioside GD1a molecular species with primarily C18:0 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1556]Formal Name: ganglioside GD1a, disodium salt. CAS Number: 12707-58-3. Synonyms: Disialoganglioside GD1a, Ganglioside B1, Ganglioside G3. Molecular Formula: C84H146N4O39 . 2Na (for stearoyl). Formula Weight: 1836.1. Purity: >98%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: Soluble. SMILES: O[C@H]1[C@@H](O[C@@H]([C@H](O)[C@@H]1O[C@]2(O[C@H]([C@@H]([C@H](C2)O)NC(C)=O)[C@@]([H])([C@]([H])(O)CO)O)C([O-])=O)CO)O[C@H]3[C@H]([C@H](O[C@H]([C@@H]3NC(C)=O)O[C@@H]4[C@@H]([C@H]([C@@H](O[C@@H]4CO)O[C@H]5[C@@H]([C@H]([C@@H](O[C@@H]5CO)OC[C@@]([H])([C@](O)(/C=C/CCCCCCCCCCCCC)[H])NC(CCCCCCCCCCCCCCCCC)=O)O)O)O)O[C@]6(O[C@H]([C@@H]([C@H](C6)O)NC(C)=O)[C@@]([H])([C@]([H])(O)CO)O)C([O-])=O)CO)O.[Na+].[Na+]. InChi Code: InChI=1S/C84H148N4O39.2Na/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-58(103)88-48(49(98)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2)44-116-78-67(109)66(108)70(56(42-93)119-78)121-80-69(111)76(127-84(82(114)115)37-51(100)60(86-46(4)96)74(125-84)63(105)53(102)39-90)71(57(43-94)120-80)122-77-61(87-47(5)97)72(64(106)54(40-91)117-77)123-79-68(110)75(65(107)55(41-92)118-79)126-83(81(112)113)36-50(99)59(85-45(3)95)73(124-83)62(104)52(101)38-89,,/h32,34,48-57,59-80,89-94,98-102,104-111H,6-31,33,35-44H2,1-5H3,(H,85,95)(H,86,96)(H,87,97)(H,88,103)(H,112,113)(H,114,115),,/q,2*+1/p-2/b34-32+,,/t48-,49+,50-,51-,52+,53+,54+,55+,56+,57+,59+,60+,61+,62+,63+,64-,65-,66+,67+,68+,69+,70+,71-,72+,73+,74+,75-,76+,77-,78+,79-,80-,83-,84-,,/m0../s1. InChi Key: SIAUXRPLFQUMFE-ZKSQSZPPSA-L.
Keywords: | Ganglioside B1, Ganglioside G3, ganglioside GD1a, disodium salt |
Supplier: | Cayman Chemical |
Supplier-Nr: | 15585 |
Properties
Application: | TLR2 coreceptor |
MW: | 1836.1 D |
Formula: | C84H146N4O39 . 2Na (stearoyl) |
Purity: | >98% |
Format: | Solid |
Database Information
CAS : | 12707-58-3| Matching products |
KEGG ID : | K10159 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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