Galangin

Light yellow powder. Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (10mg/ml). Chemical. CAS: 548-83-4. Formula: C15H10O5. MW: 270.24. Galangin is a flavonoid naturally found in herbs used in traditional medicine. It has diverse biological activities, including potent antioxidant, anti-inflammatory, antiobesity, antidiabetic, anti-cancer, neuroprotective, antiviral and antibacterial properties. Galangin has anti-inflammatory actions related to suppression of signaling through NF-kappa/NRLP3 pathway. Galangin induces apoptosis and autophagy in different cancer cells. It is a TRPC5 inhibitor, inhibiting Ca2+ entry into TRPC5 expressing cells. Galangin as a potential DPP-4 inhibitor that improves insulin-stimulated skeletal muscle glucose uptake.